Helping leadership teams make better commercial decisions, with confidence.
40folds builds digital twins of a company’s commercial engine. We bring methods proven over two decades in biomedical research to the boardroom, so that finance, marketing and sales can agree on what drives the business — and where to invest next.
Founded
2025
Paris, France
Incubated at
Station F
INSEAD Launchpad programme
Backed by
Acurio Ventures
Pre-seed investor
Our mission
Give every executive committee one trusted view of what drives growth.
Today, the most consequential investment questions — why results are above or below plan, what a launch really delivered, how to reallocate budgets — are answered by department-owned analyses that rarely agree. We replace them with one consistent, independently validated model of the business, whose uncertainty is explicit and whose recommendations a CFO can defend.
Our vision
Digital twins, trusted in medicine and aerospace, as standard practice in business.
Mission-critical industries do not take decisions on a single, unvalidated model. We believe commercial decisions deserve the same discipline: a living representation of the business, governed by its own economic laws, refreshed continuously and used by leadership to plan, test and allocate resources.
Leadership
Experience from consulting, industry and science.
Rares Rusu, MBA
Co-founder & Chief Executive Officer
Twenty years in C-level strategy and budget-allocation discussions. Four years at McKinsey & Company, then fourteen years at Google — as Marketing Director for Central and Eastern Europe and CFO for Southern Europe. Author of a Google white paper on measuring marketing ROI in net-profit terms. INSEAD MBA.
PhD in Biomedical Engineering and twenty years of Bayesian statistics, with more than 1,000 citations. Developed disease-progression models and clinical digital twins whose methods now underpin the 40folds optimisation engine.
PhD-trained applied scientist specialising in machine learning, hybrid modelling and digital twins. Turns research-grade models into robust, production-ready systems for our clients.
Economist and former financial analyst, and 2x co-founder with ten years building and running operations-intensive businesses. Leads administration, finance, people and compliance at 40folds.